en تخصصي Special پژوهشي Research Article <aside style="box-sizing: border-box; font-family: Lato, Arial; word-wrap: break-word; margin-bottom: 10px; font-size: 11px;"> <p style="box-sizing: border-box; word-wrap: break-word; margin: 0px 0px 10px; font-size: 12px; text-align: justify;"><span style="box-sizing: border-box; word-wrap: break-word; font-weight: 700;">Background:</span>&nbsp;Drug addiction, obsessive compulsive disorders (OCD), and other anxiety disorders are the disorders most commonly found in patients with bipolar disorder.</p> </aside> <aside style="box-sizing: border-box; font-family: Lato, Arial; word-wrap: break-word; margin-bottom: 10px; font-size: 11px;"> <p style="box-sizing: border-box; word-wrap: break-word; margin: 0px 0px 10px; font-size: 12px; text-align: justify;"><span style="box-sizing: border-box; word-wrap: break-word; font-weight: 700;">Objectives:</span>&nbsp;The purpose of this study was to identify the factors affecting the risk of drug addiction, obsessive compulsive disorders, and other anxiety disorders in patients with bipolar disorder.</p> </aside> <aside style="box-sizing: border-box; font-family: Lato, Arial; word-wrap: break-word; margin-bottom: 10px; font-size: 11px;"> <p style="box-sizing: border-box; word-wrap: break-word; margin: 0px 0px 10px; font-size: 12px; text-align: justify;"><span style="box-sizing: border-box; word-wrap: break-word; font-weight: 700;">Patients and Methods:</span>&nbsp;In this retrospective cohort study, the medical records of 400 patients with bipolar disorder hospitalized in Hamadan, Iran, between 2008 and 2014 were examined. Patient information, including demographic characteristics and comorbidity, was collected. A data analysis was performed using a separate logistic regression for each disorder. The statistical package used was STATA software version 11. A P-value of less than 0.05 was considered statistically significant.</p> </aside> <aside style="box-sizing: border-box; font-family: Lato, Arial; word-wrap: break-word; margin-bottom: 10px; font-size: 11px;"> <p style="box-sizing: border-box; word-wrap: break-word; margin: 0px 0px 10px; font-size: 12px; text-align: justify;"><span style="box-sizing: border-box; word-wrap: break-word; font-weight: 700;">Results:</span>&nbsp;The mean (SD) age of the patients with bipolar disorder was 34.62 (1.68) years. Of the 400 patients with bipolar disorder, 135 (33.75%) patients had anxiety disorders, 67 (16.8%) patients suffered from drug addiction, and 45 (11%) patients had OCD. An association was established between drug addiction and OCD, and gender (P &le; 0.05). The ORs of anxiety disorders, drug addiction, and OCD were 1.05 (95% CI = 0.65 - 1.68), 0.26 (95% CI = 0.10 - 0.63), and 2.33 (95% CI = 1.21 - 4.48) for women, and 0.92 (95% CI = 0.52 - 2.13), 3.01 (95% CI = 1.64 - 5.55), and 0.64 (95% CI = 0.25 - 1.62) for the patients who smoked, respectively. In addition, there was no significant association between the different disorders and age, marital status, history of relapse, and history of suicide.</p> </aside> <aside style="box-sizing: border-box; font-family: Lato, Arial; word-wrap: break-word; margin-bottom: 10px; font-size: 11px;"> <p style="box-sizing: border-box; word-wrap: break-word; margin: 0px 0px 10px; font-size: 12px; text-align: justify;"><span style="box-sizing: border-box; word-wrap: break-word; font-weight: 700;">Conclusions:</span>&nbsp;The results showed that there was a greater risk of anxiety disorders with bipolar disorder than other disorders. While women with bipolar disorder were at higher risk of anxiety disorders and OCD, men were at greater risk of drug addiction.</p> </aside> Anxiety Disorders, Bipolar Disorder, Comorbidity, Drug Addiction, Obsessive Compulsive Disorder, Logistic Regression 12 16 http://ajnpp.umsha.ac.ir/browse.php?a_code=A-10-2-45&slc_lang=en&sid=1 Roya Najafi Vosough 1003194753284600213 1003194753284600213 No Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran Ali Ghaleiha 1003194753284600214 1003194753284600214 No Behavioral Disorders and Substance Abuse Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran Javad Faradmal 1003194753284600215 1003194753284600215 No Modeling of Noncommunicable Disease Research Canter, Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran Hossein Mahjub mahjub@umsha.ac.ir 1003194753284600216 1003194753284600216 Yes Research Center for Health Sciences and Department of Biostatistics, School of Public Health, Hamadan University of Medical Sciences, Hamadan, IR Iran