en Clinical Psychology پژوهشي Research Article <strong>Background</strong>: Psychological hardiness and social support are two necessary health-elevating factors that strengthen individuals to remain both psychologically and physically healthy despite encountering negative life events.&nbsp;<br> <strong>Objectives</strong>: This study aimed at investigating the relationship between psychological hardiness and social support in women with breast cancer.<br> <strong>Materials and Methods</strong>: This descriptive study was conducted on 110 women with breast cancer in the Shafa Hospital of Ahvaz, Iran in 2018-2019. The personal/demographic/illness questionnaire, Kobasa Psychological Hardiness Questionnaire, and Multidimensional Scale of Perceived Social Support were research tools. Data were analyzed by&nbsp;the one-sample t-test, analysis of variance, and Pearson correlation at a significance level of P<0.05.&nbsp;<br> <strong>Results</strong>: There was a significant positive correlation between perceived social support and psychological hardiness (r=0.045; P<0.05) and perceived social support and commitment (r=0.469; P<0.05). Also, there was a positive and significant correlation between perceived social support and control (r=0.429; P<0.05) and perceived social support and challenging (r=0.266; P<0.05).&nbsp;<br> <strong>Conclusion</strong>: The results showed that psychological hardiness and social supports have a significant relationship; therefore, healthcare providers can use these personality attributes in their care plans for better coping strategies. Perceived social support and psychological hardness can be effective in progressing the patients&rsquo; health and should be considered as effective moderating factors in their therapy process. Social support, Psychological hardiness, Breast cancer 159 164 http://ajnpp.umsha.ac.ir/browse.php?a_code=A-10-191-1&slc_lang=en&sid=1 Mahsa Jalali khajeh8794@gmail.com 10031947532846003758 10031947532846003758 No Department of Psychology, Faculty of Educational Sciences & Psychology, Islamic Azad University, Buin Zahra Branch, Karaj, Iran. Masumeh Rahimi 10031947532846003759 10031947532846003759 Yes Department of Psychology, Faculty of Educational Sciences & Psychology, University of Kharazmi, Tehran, Iran.