en Health Education and Promotion پژوهشي Research Article <span style="font-size:12px;"><span style="font-family:Tahoma;"><span style="line-height:150%"><b><span style="line-height:150%">Background and Objective: </span></b><span style="line-height:150%">The present study aimed to examine the effect of Acceptance and Commitment Therapy (ACT) on pain perception and self-care in individuals with migraines.</span></span><br> <span style="line-height:150%"><b><span style="line-height:150%">Materials and Methods: </span></b>A quasi-experimental pretest&ndash;posttest design with a control group was conducted at Shahid Fahmideh Hospital, Tehran, Iran, from 2023 to 2024. The sample consisted of 24 <span style="line-height:150%">(1</span>2<span style="line-height:150%"> per group)</span> women with migraine headaches who were purposively selected and assigned to the intervention and control groups. <span style="line-height:150%">The experimental group received eight 90-min ACT sessions; the control group received no intervention. Pain perception and self-care were measured using the Short-Form McGill Pain Questionnaire and the Madah Questionnaire. Moreover, data were analyzed by</span> <span style="line-height:150%">multivariate analysis of covariance (MANCOVA).</span><span lang="AR-IQ" dir="RTL" style="font-family:&quot;Times New Roman&quot;,serif"></span></span><br> <span style="line-height:150%"><b><span style="line-height:150%">Results: </span></b><span style="line-height:150%">The findings indicated that the effect of group assignment on overall pain perception and its components&mdash;including sensory, affective, evaluative, and self-care dimensions was significant. After controlling for pretest scores, a significant difference between the groups was found (P<0.01)</span></span><br> <span style="line-height:150%"><b><span style="line-height:150%">Conclusions: </span></b><span style="line-height:150%">The findings indicate that ACT reduces pain perception and improves self-care behaviors in women with migraines, suggesting it may be an effective psychological intervention for this population.</span></span></span></span><br> &nbsp; Acceptance and Commitment Therapy (ACT), Migraine, Pain perception, Self-care 0 0 http://ajnpp.umsha.ac.ir/browse.php?a_code=A-10-2651-1&slc_lang=en&sid=1 Najme Fathalizade se.fathalizade@iau.ac.ir 10031947532846009030 10031947532846009030 No Department of Psychology, Ro.C., Islamic Azad University, Roudehen, Iran. Fariba Bashardoost Tajali faribabashardoost@iau.ac.ir 10031947532846009029 10031947532846009029 Yes Department of Psychology, Ro.C., Islamic Azad University, Roudehen, Iran. Narges Babakhani nargesbabakhani@iau.ac.ir 10031947532846009031 10031947532846009031 No Department of Psychology, Ro.C., Islamic Azad University, Roudehen, Iran.